Entropy-driven homochiral self-sorting of a dynamic library. Issue 30 (31st March 2017)
- Record Type:
- Journal Article
- Title:
- Entropy-driven homochiral self-sorting of a dynamic library. Issue 30 (31st March 2017)
- Main Title:
- Entropy-driven homochiral self-sorting of a dynamic library
- Authors:
- Atcher, Joan
Bujons, Jordi
Alfonso, Ignacio - Abstract:
- Abstract : The efficient homochiral self-sorting of pseudopeptidic macrocycles, observed from a simple dynamic library, is driven by entropy. Abstract : A dynamic mixture of stereoisomeric macrocycles derived from glutamic acid displayed a homochiral self-selection when increasing the acetonitrile content of the aqueous mixed medium. The homochiral self-sorting required the anionic form of the side chains and increased at higher temperature, implying an entropic origin. Conformational analysis (NMR and MD simulations) allowed us to explain the observed behaviour. The results show that entropy can play a role in the homochiral self-sorting in adaptive bio-inspired chemical systems.
- Is Part Of:
- Chemical communications. Volume 53:Issue 30(2017)
- Journal:
- Chemical communications
- Issue:
- Volume 53:Issue 30(2017)
- Issue Display:
- Volume 53, Issue 30 (2017)
- Year:
- 2017
- Volume:
- 53
- Issue:
- 30
- Issue Sort Value:
- 2017-0053-0030-0000
- Page Start:
- 4274
- Page End:
- 4277
- Publication Date:
- 2017-03-31
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c7cc01153a ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 2557.xml