Clinical characteristics, management and outcomes of patients with chronic heart failure: Results from the heart function assessment registry trial in Saudi Arabia (HEARTS-chronic). (15th May 2017)

• Record Type: Journal Article
• Authors: Alhabeeb, Waleed; Elasfar, Abdelfatah; AlBackr, Hanan; AlShaer, Fayez; Almasood, Ali; Alfaleh, Hussam; Kashour, Tarek; Hersi, Ahmad; Asfina, Kazi Nur; Altaradi, Hani; AlShaqhaa, Waleed; Alayoubi, Fakhr; AlHabib, Khalid F
• Is Part Of: International journal of cardiology. Volume 235(2017)
• Page Start: 94
• Page End: 99
• Publication Date: 2017-05-15
• Subjects: Chronic heart failure -- Registry -- Middle East; Cardiology -- Periodicals; Electronic journals; 616.12
• DOI: 10.1016/j.ijcard.2017.02.087
• Languages: English
• ISSNs: 0167-5273

Abstract

Abstract: Background: Several registries have described patients hospitalized with heart failure (HF), but only few looked at outpatients in the ambulatory setting mostly without long-term follow-up. We sought to determine the clinical characteristics, management, and 1-year outcomes of patients with chronic HF in Saudi Arabia. Methods: Part of a prospective multicenter nationwide registry; HEart function Assessment Registry Trial in Saudi Arabia (HEARTS) and included chronic HF patients referred to four HFCs between September 2009 and December 2011. Results: We enrolled 685 patients with mean age 55.66 ± 15.97 years, 70.1% were men and 96.1% were Saudis. The main etiologies of HF were CAD (38.8%), dilated cardiomyopathy (36.5%), and hypertension (10.5%). Severe left ventricular dysfunction was present in 70.6% and median NT-proBNP was 2934.37 pg/ml. The prescription rates of evidence based therapies (EBTs) before admission to HFC, at discharge from 1st clinic visit, and at 1-year follow up were 90%, 91% and 94% for beta-blockers, 79%, 80%, and 86% for ACEi/ARBs and 44%, 45%, and 42% for aldosterone antagonists; respectively. ICD was inserted in 21.9% and CRT in 6.6% at enrollment and increased to 29.1% and 8.8% after one year respectively. The all-cause mortality rate at 1 year was 9% and 93.7% of which was cardiac-related. The all-cause one-year hospitalization rate was 39% and the total emergency room visit rate was 50%. Conclusions: Chronic HF patients in Saudi Arabia are younger, commonly have severe LV systolic dysfunction and have relatively high annual mortality and re-hospitalization rates.