Safety and efficacy of laparoscopic wedge gastrectomy for large gastrointestinal stromal tumors. Issue 4 (April 2017)

• Record Type: Journal Article
• Authors: Milone, M.; Elmore, U.; Musella, M.; Parise, P.; Zotti, M.C.; Bracale, U.; Di Lauro, K.; Manigrasso, M.; Milone, F.; Rosati, R.
• Is Part Of: European journal of surgical oncology. Volume 43:Issue 4(2017:Apr.)
• Page Start: 796
• Page End: 800
• Publication Date: 2017-04
• Subjects: Gastrointestinal stromal tumor -- GIST -- Laparoscopic -- Wedge gastrectomy -- Gastrectomy; Oncology -- Periodicals; Cancer -- Surgery -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- surgery -- Periodicals; Cancer -- Chirurgie -- Périodiques; Cancérologie -- Périodiques; Oncologie; Chirurgie (geneeskunde); Electronic journals; Electronic journals -- Sciences; Electronic journals -- Medicine; Electronic journals; 616.994059005
• DOI: 10.1016/j.ejso.2017.01.005
• Languages: English
• ISSNs: 0748-7983

Abstract

Abstract: Background: Although the feasibility of minimally invasive resection of small gastric GISTs is well established, less is known about safety and efficacy of laparoscopic surgery for large tumors. Methods: A retrospective analysis was performed, using a prospectively maintained comprehensive database. Patients were divided into two groups according to tumor size: Case group with tumors > 5 cm and control group with tumors <5 cm. Hospital charts were reviewed, and various outcome measures recorded, including operative time, estimated operative blood loss, post-operative leak, stasis, infection and recurrence. Results: No tumors were ruptured during surgical manipulation and no major morbidity or mortality occurred in either group. Operative time (75, 8 ± 33, 1 min in large cases vs 75, 8 ± 33, 1 min in small cases) was similar in both groups (p = 0, 61). The incidence of post-operative complications did not differ between the two groups. In details there were 21 out of 25 (84%) uncomplicated cases among small GISTs versus 17 out of 24 (70, 8%) uncomplicated cases among large GISTs (p = 0, 32). Conclusion: This matched-pair case control study demonstrates that laparoscopic wedge resection for large gastric GISTs is safe and effective, as demonstrated for small tumors.