Five-component synthesis of dihydropyridines based on diketene. Issue 15 (13th April 2017)
- Record Type:
- Journal Article
- Title:
- Five-component synthesis of dihydropyridines based on diketene. Issue 15 (13th April 2017)
- Main Title:
- Five-component synthesis of dihydropyridines based on diketene
- Authors:
- Rezvanian, Atieh
Heravi, Majid M.
Shaabani, Zahra
Tajbakhsh, Mahmood - Abstract:
- Abstract: A novel five-component strategy involving commercially available diketene, primary amines, malononitrile and various benzaldehydes for the synthesis of densely functionalized 1, 4-dihydropyridines in good yields was achieved. The reaction pathway involves a sequential ring-opening of diketene/enamine formation/Knoevenagel-condensation/Michael addition and 6- exo-tet cyclization, resulting in multiple bond-formation events including two C–C and three C–N bonds ultimately leading to the formation of the respective 1, 4-dihydropyridines. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 73:Issue 15(2017)
- Journal:
- Tetrahedron
- Issue:
- Volume 73:Issue 15(2017)
- Issue Display:
- Volume 73, Issue 15 (2017)
- Year:
- 2017
- Volume:
- 73
- Issue:
- 15
- Issue Sort Value:
- 2017-0073-0015-0000
- Page Start:
- 2009
- Page End:
- 2013
- Publication Date:
- 2017-04-13
- Subjects:
- Diketene -- 1, 4-dihydropyridines -- Primary amine -- Five-component reaction
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2017.02.027 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1891.xml