Triterpenoid glycosides from Ladenbergia hexandra Klotzsch. (April 2017)

• Record Type: Journal Article
• Authors: Furukawa, Megumi; Kamo, Satoshi; Makino, Mitsuko; Kurita, Masahiro; Tabata, Keiichi; Matsuzaki, Keiichi; Suzuki, Takashi; Uchiyama, Taketo
• Is Part Of: Phytochemistry. Volume 136(2017)
• Page Start: 147
• Page End: 155
• Publication Date: 2017-04
• Subjects: Ladenbergia hexandra -- Rubiaceae -- Triterpene glycoside -- β-D-allose -- 6-Deoxy-β-D-allose -- β-D-quinovose -- Glycosyl iodide; Botanical chemistry -- Periodicals; Biochemistry -- Periodicals; Botany -- Periodicals; Chimie végétale -- Périodiques; 572.2
• DOI: 10.1016/j.phytochem.2017.01.014
• Languages: English
• ISSNs: 0031-9422

Abstract

Abstract: From the bark of Ladenbergia hexandra Klotzsch, ten triterpenoid glycosides were isolated along with five known compounds, and their structures were determined based on extensive NMR and mass spectroscopic, GC and HPLC analyses. Some triterpenoid glycosides contained 6-deoxy-D-allose or D-allose as a sugar moiety. The absolute stereochemical assignment of the sugars was determined by comparison with synthetic samples, as well as by GC and HPLC analysis. Graphical abstract: From the bark of Ladenbergia hexandra Klotzsch, ten triterpenoid glycosides were isolated and identified along with five known compounds Highlights: Constituents of Ladenbergia hexandra ethanol extracts were studied. Ten triterpenoid glycosides were isolated along with five known compounds. Some of the triterpenoid glycosides contained a rare 6-deoxy-D-allose moiety. A synthetic preparation of a 6-deoxy sugar was performed.