DNA Nanostructures: Tetrahedral DNA Nanostructure: A Potential Promoter for Cartilage Tissue Regeneration via Regulating Chondrocyte Phenotype and Proliferation (Small 12/2017). Issue 12 (March 2017)

• Record Type: Journal Article
• Authors: Shao, Xiaoru; Lin, Shiyu; Peng, Qiang; Shi, Sirong; Wei, Xueqin; Zhang, Tao; Lin, Yunfeng
• Is Part Of: Small. Volume 13:Issue 12(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-03
• Subjects: chondrocytes -- nanomaterials -- notch signaling pathway -- self‐assembly -- tetrahedral DNA nanostructures; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201770070
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : A tetrahedral DNA nanostructure (TDN), a novel type of DNA nanomaterials, is able to regulate chondrocyte phenotype and promote chondrocyte proliferation, as presented in article number 1602770 by Yunfeng Lin and co‐workers. The regulation of cell phenotype is related with down‐regulating the Notch signaling pathway. This discovery sheds light on the potential of TDNs in future medicine, especially cartilage regeneration.