An infant with diabetes mellitus: Is it always T1DM?. (March 2017)

• Record Type: Journal Article
• Authors: Mukherjee, Soham; Rastogi, Ashu; Venkatesan, Radha; Sundaramoorthi, Gopi; Mohan, Viswanathan; Bhansali, Anil
• Is Part Of: Diabetes research and clinical practice. Volume 125(2017)
• Page Start: 62
• Page End: 64
• Publication Date: 2017-03
• Subjects: Neonatal diabetes novel ABCC 8 gene mutation; Diabetes -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462
• DOI: 10.1016/j.diabres.2016.07.014
• Languages: English
• ISSNs: 0168-8227

Abstract

Highlights: Novel heterozygous mutation Arg992Cys in ABCC 8 gene, causing neonatal diabetes in an infant. He was initiated on insulin therapy, but later successfully switched to oral anti-diabetic drug. On follow-up he was found to have permanent form of neonatal diabetes. Abstract: Here we describe a 2 1/2 month old infant with neonatal diabetes mellitus (NDM) who was initially misdiagnosed to have T1DM and initiated on insulin. He was found to have a novel heterozygous mutation Arg992Cys in ABCC 8 gene and successfully switched to oral anti-diabetic drug.