Systolic myocardial volume gain in dilated, hypertrophied and normal heart. CMR study. Issue 4 (April 2017)

• Record Type: Journal Article
• Authors: Mazurkiewicz, Ł.; Orłowska-Baranowska, E.; Petryka, J.; Śpiewak, M.; Gawor, M.; Miłosz-Wieczorek, B.; Werys, K.; Małek, Ł.A.; Marczak, M.; Grzybowski, J.
• Is Part Of: Clinical radiology. Volume 72:Issue 4(2017)
• Page Start: 286
• Page End: 292
• Publication Date: 2017-04
• Subjects: Medical radiology -- Periodicals; Radiotherapy -- Periodicals; Radiotherapy -- Periodicals; Radiology -- Periodicals; Societies, Medical -- Periodicals; Medical radiology; Radiotherapy; Electronic journals; Periodicals; 616.0757
• DOI: 10.1016/j.crad.2016.10.024
• Languages: English
• ISSNs: 0009-9260

Abstract

Abstract : Aim: To investigate changes in myocardial tissue volume during the cardiac cycle to verify the hypothesis of non-compressibility of the myocardium in healthy individuals (HI) as well as in patients with hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), and aortic stenosis (AS). Materials and methods: The study group included 30 HI, and patients with HCM ( n =110), DCM ( n =89), and AS ( n =78). Left ventricular (LV) function, end-diastolic, and end-systolic volumes were calculated based on cardiac magnetic resonance imaging (CMR) for all participants. Results: End-systolic myocardial volumes were higher than end-diastolic in both controls (91.2±26.6 versus 85.1±24.3 ml, p <0.001) and in all patient groups: HCM (214.3±81.6 versus 176±64.2 ml, p <0.01), DCM (128.4±43.1 versus 115.4±42.9 ml, p <0.001) and AS (155.1±37.1 versus 129.4±34.6 ml, p <0.001). HCM and AS patients had significantly higher systolic volume gain than HI (21.5±8.3 versus 10.6±6.3%, p <0.01 and 18.3±5.7 versus 10.6±6.3% p =0.013, respectively). Conversely, DCM patients had lesser increases in myocardial systolic volume than HCM patients (11.2±4.8% versus 21.5±8.3, p =0.01) and AS patients (11.2±4.8% versus 18.3±5.7, p =0.02). No differences were found in systolic volume gain between AS and HCM patients ( p =ns) or between DCM patients and HI ( p =ns). Conclusion: End-systolic myocardial volume was significantly higher than end-diastolic volume in all subsets of patients. The systolic volume gain was greater in individuals with hypertrophy than in those without. Highlights: Healthy individuals were found to have higher systolic myocardial volume than diastolic. Systolic myocardial volume was higher than diastolic in all subsets of patients. HCM and AS patients had higher myocardial volume gains than HI and DCM patients. No difference in systolic volume gain was found between HI and DCM subjects. The magnitude of volume increase in systole was similar in patients with hypertrophy.