A MnO2 nanosheet-assisted GSH detection platform using an iridium(iii) complex as a switch-on luminescent probe. Issue 14 (31st January 2017)

• Record Type: Journal Article
• Authors: Dong, Zhen-Zhen; Lu, Lihua; Ko, Chung-Nga; Yang, Chao; Li, Shengnan; Lee, Ming-Yuen; Leung, Chung-Hang; Ma, Dik-Lung
• Is Part Of: Nanoscale. Volume 9:Issue 14(2017)
• Page Start: 4677
• Page End: 4682
• Publication Date: 2017-01-31
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/c6nr08357a
• Languages: English
• ISSNs: 2040-3364

Abstract

Abstract : A rapid and sensitive detection platform for GSH has been constructed by combining a MnO2 nanosheet with a luminescent iridium(iii ) complex [Ir(Cl-phq)2 (Cl-phen)] + . Abstract : A rapid and sensitive detection platform for GSH has been constructed by combining a MnO2 nanosheet with a luminescent iridium(iii ) complex [Ir(Cl-phq)2 (Cl-phen)] + . The MnO2 nanosheet was prepared by using a facile one-step approach and was characterized by TEM. The luminescence intensity of the detection platform responded linearly with the GSH concentration from 1 to 200 μM ( R 2 = 0.9951), and the detection limit for GSH was 0.13 μM. More importantly, practical application of the detection platform for visualizing the intracellular GSH distribution in living zebrafish has also been demonstrated.