Nanomaterials‐based biosensors for detection of microorganisms and microbial toxins. Issue 4 (27th October 2016)

• Record Type: Journal Article
• Authors: Sutarlie, Laura; Ow, Sian Yang; Su, Xiaodi
• Is Part Of: Biotechnology journal. Volume 12:Issue 4(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2016-10-27
• Subjects: Biosensors -- Microbial toxins -- Microorganisms -- Nanomaterials -- Nanosensors; Biotechnology -- Periodicals; 660.605
• DOI: 10.1002/biot.201500459
• Languages: English
• ISSNs: 1860-6768

Abstract

Abstract: Detection of microorganisms and microbial toxins is important for health and safety. Due to their unique physical and chemical properties, nanomaterials have been extensively used to develop biosensors for rapid detection of microorganisms with microbial cells and toxins as target analytes. In this paper, the design principles of nanomaterials‐based biosensors for four selected analyte categories (bacteria cells, toxins, mycotoxins, and protozoa cells), closely associated with the target analytes' properties is reviewed. Five signal transducing methods that are less equipment intensive (colorimetric, fluorimetric, surface enhanced Raman scattering, electrochemical, and magnetic relaxometry methods) is described and compared for their sensory performance (in term oflimit of detection, dynamic range, and response time) for all analyte categories. In the end, the suitability of these five sensing principles for on‐site or field applications is discussed. With a comprehensive coverage of nanomaterials, design principles, sensing principles, and assessment on the sensory performance and suitability for on‐site application, this review offers valuable insight and perspective for designing suitable nanomaterials‐based microorganism biosensors for a given application. Abstract : The detection of microorganisms and their toxins in food and the environment are important for health and safety reasons. This review summarizes the various nanoparticle‐based methods to detect microorganisms and their toxins from environmental samples as well as the implications and possibilities for adaptation of these methods into an on‐site rapid detection system. This article is part of an AFOB (Asian Federation of Biotechnology) Special issue. To learn more about the AFOB, visitwww.afob.org .