Green and Practical Oxidative Deoximation of Oximes to Ketones or Aldehydes with Hydrogen Peroxide/Air by Organoselenium Catalysis. Issue 7 (15th March 2017)

• Record Type: Journal Article
• Authors: Jing, Xiaobi; Yuan, Dandan; Yu, Lei
• Is Part Of: Advanced synthesis & catalysis. Volume 359:Issue 7(2017)
• Page Start: 1194
• Page End: 1201
• Publication Date: 2017-03-15
• Subjects: aldehydes -- deoximation -- ketones -- organoselenium catalysis -- oximes; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201601353
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: Organoselenium‐catalyzed oxidative deoximations afforded ketones and aldehydes under mild conditions. The reactions employ hydrogen peroxide and air as clean oxidants and lead to a waste‐free and metal‐free deprotection protocol for carbonyl protection strategies as well as the green synthesis of ketones and aldehydes. The mechanisms of this interesting organoselenium‐catalyzed reaction have been investigated by control experiments as well as the selenium 77 nuclear magnetic resonance ( 77 Se NMR) tests. This novel reaction largely expands the application scope of organoselenium catalysis. Abstract :