CADASIL: two new cases with intracerebral hemorrhage. Issue 4 (7th March 2017)

• Record Type: Journal Article
• Authors: Zhang, Chen; Li, Wei; Li, Shaowu; Niu, Songtao; Wang, Xingao; Tang, Hefei; Yu, Xueying; Chen, Bin; Shi, Yuzhi; Chen, Qihua; Guo, Liying; Pan, Yunzhu; Wang, Yilong; Zhang, Zaiqiang
• Is Part Of: Annals of clinical and translational neurology. Volume 4:Issue 4(2017)
• Page Start: 266
• Page End: 271
• Publication Date: 2017-03-07
• Subjects: Nervous system -- Diseases -- Periodicals; Neurology -- Periodicals; 616.8005
• DOI: 10.1002/acn3.400
• Languages: English
• ISSNs: 2328-9503

Abstract

Abstract: Whether cerebral autosomal‐dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a risk factor for spontaneous intracerebral hemorrhage (ICH) and influences outcomes remains unclear. In this study, we report two cases of CADASIL presenting with cerebral hemorrhages. These cases suggest that a CADASIL vasculopathy by itself mainly results in ICH, as indicated by slight vascular risk factors and prominent neuroimaging abnormalities, suggesting that CADASIL should be considered a risk factor for ICH. Interestingly, decreased perihematomal edema was noted in ICH patients with CADASIL in this study.