Asymmetric hydroarylation of vinyl ethers catalyzed by a hydroxoiridium complex: azoles as effective directing groups. Issue 18 (17th February 2017)

• Record Type: Journal Article
• Authors: Yamauchi, Daisuke; Nishimura, Takahiro; Yorimitsu, Hideki
• Is Part Of: Chemical communications. Volume 53:Issue 18(2017)
• Page Start: 2760
• Page End: 2763
• Publication Date: 2017-02-17
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc00238f
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Asymmetric hydroarylation of vinyl ethers using azoles as directing groups was realized by use of a hydroxoiridium/chiral phosphine catalyst. Abstract : Catalytic asymmetric hydroarylation of vinyl ethers using 2-aryl-substituted azoles containing an N–H bond as directing groups was realized by use of a hydroxoiridium/chiral phosphine catalyst. The reaction proceeded via C–H activation of the aromatic ring to give high yields of the corresponding addition products with high branch- and enantioselectivity.