A fresh look at the use of nonparametric analysis in actimetry. (April 2015)

• Record Type: Journal Article
• Authors: Gonçalves, BSB; Adamowicz, Taísa; Louzada, Fernando Mazzilli; Moreno, Claudia Roberta; Araujo, John Fontenele
• Is Part Of: Sleep medicine reviews. Volume 20(2015)
• Page Start: 84
• Page End: 91
• Publication Date: 2015-04
• Subjects: Circadian -- Homeostatic -- Functional model -- Sleep -- Fragmentation -- Synchronization -- Amplitude -- Rest-activity; Sleep disorders -- Periodicals; Sleep Disorders -- Periodicals; Sommeil, Troubles du -- Périodiques; Electronic journals; 616.8498
• DOI: 10.1016/j.smrv.2014.06.002
• Languages: English
• ISSNs: 1087-0792

Abstract

Summary: Actimetry has been used to estimate the sleep–wake cycle instead of the rest-activity rhythm. Although algorithms for assessing sleep from actimetry data exist, it is useful to analyze the rest-activity rhythm using nonparametric methods. This would then allow rest-activity rhythm stability, fragmentation and amplitude to be quantified. In addition, sleep and wakefulness efficiency can be quantified separately. These variables have been used in studies analyzing the effect of age, diseases and their respective treatments on human circadian rhythmicity. In this study, we carried out a comprehensive analysis of the main results from published articles and devised a functional model of interaction among the several components involved in generating the sleep–wake cycle. The nonparametric variables render it possible to infer the main characteristics of circadian rhythms, such as synchronization with a zeitgeber, and its amplitude and robustness.