Anhydrides from aldehydes or alcohols via oxidative cross-coupling. (2nd November 2016)

• Record Type: Journal Article
• Authors: Gaspa, Silvia; Amura, Ida; Porcheddu, Andrea; De Luca, Lidia
• Is Part Of: New journal of chemistry. Volume 41:Number 3(2017)
• Page Start: 931
• Page End: 939
• Publication Date: 2016-11-02
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/c6nj02625g
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : A novel type of oxidative cross-coupling was developed to prepare symmetrical and mixed anhydrides from aldehydes or alcohols using trichloroisocyanuric acid (TCCA). Abstract : A novel type of metal-free oxidative cross-coupling for the synthesis of symmetrical and mixed anhydrides from aldehydes or benzylic alcohols has been developed. The aldehydes or alcohols were converted in situ into their corresponding acyl chlorides, which were then reacted with an array of carboxylic acids. The methodology has a general applicability, and was successfully employed to prepare either aromatic or aliphatic symmetrical anhydrides and mixed anhydrides, which are very unstable compounds.