Regioselective SN2 reactions for rapid syntheses of azido-inositols by one-pot sequence-specific nucleophilysis. Issue 28 (22nd March 2017)
- Record Type:
- Journal Article
- Title:
- Regioselective SN2 reactions for rapid syntheses of azido-inositols by one-pot sequence-specific nucleophilysis. Issue 28 (22nd March 2017)
- Main Title:
- Regioselective SN2 reactions for rapid syntheses of azido-inositols by one-pot sequence-specific nucleophilysis
- Authors:
- Ravi, Arthi
Hassan, Syed Zahid
Vanikrishna, Ajithkumar N.
Sureshan, Kana M. - Abstract:
- Abstract : Sequential nucleophilysis of myo -inositol-disulfonate provides easy access to azido-inositols. Abstract : Triflates of myo -inositol undergo facile solvolysis in DMSO and DMF yielding SN 2 products substituted with O -nucleophiles; DMF showed slower kinetics. Axial O -triflate undergoes faster substitution than equatorial O -triflate. By exploiting this difference in kinetics, solvent-tuning and sequence-controlled nucleophilysis, rapid synthesis of three azido-inositols of myo -configuration from myo -inositol itself has been achieved.
- Is Part Of:
- Chemical communications. Volume 53:Issue 28(2017)
- Journal:
- Chemical communications
- Issue:
- Volume 53:Issue 28(2017)
- Issue Display:
- Volume 53, Issue 28 (2017)
- Year:
- 2017
- Volume:
- 53
- Issue:
- 28
- Issue Sort Value:
- 2017-0053-0028-0000
- Page Start:
- 3971
- Page End:
- 3973
- Publication Date:
- 2017-03-22
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c7cc01219e ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1429.xml