Aptamer-based biosensors for detection of lead(ii) ion: a review. Issue 13 (22nd March 2017)

• Record Type: Journal Article
• Authors: Yang, Danxing; Liu, Xiaocheng; Zhou, Yaoyu; Luo, Lin; Zhang, Jiachao; Huang, Anqi; Mao, Qiming; Chen, Xiao; Tang, Lin
• Is Part Of: Analytical methods. Volume 9:Issue 13(2017)
• Page Start: 1976
• Page End: 1990
• Publication Date: 2017-03-22
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/c7ay00477j
• Languages: English
• ISSNs: 1759-9660

Abstract

Abstract : Lead(ii ) ion (Pb 2+ ) contamination can be accumulated along the food chain and cause a serious threat to public health. Abstract : Lead(ii ) ion (Pb 2+ ) contamination can be accumulated along the food chain and cause a serious threat to public health. Plenty of research effort has thus been devoted to the development of fast, sensitive and selective biosensors for monitoring Pb 2+ . Aptamer especially Pb 2+ based DNAzymes (obtained from a large DNA library via in vitro selection) and DNA molecules are highly selective for a number of metal ions. Therefore, aptamer-based biosensors have been extensively studied for Pb 2+ ion detection with a high sensitivity. In this review, we explain the current progress of Pb 2+ aptamer-based sensors mainly in three groups: fluorescent; colorimetric; and electrochemical biosensors.