Acute and chronic flow-mediated dilation and blood pressure responses to daily intake of boysenberry juice: a preliminary study. (12th July 2013)

• Record Type: Journal Article
• Authors: Matsusima, Akito; Furuuchi, Ryo; Sakaguchi, Yoshiko; Goto, Hiroshi; Yokoyama, Tadayuki; Nishida, Hiroshi; Hirayama, Masao
• Is Part Of: International journal of food sciences and nutrition. Volume 64:Number 8(2013)
• Page Start: 988
• Page End: 992
• Publication Date: 2013-07-12
• Subjects: 4-Week intervention study -- cardiovascular risk -- short oligomeric flavanols; Food -- Analysis -- Periodicals; Nutrition -- Periodicals; 641.3
• DOI: 10.3109/09637486.2013.812617
• Languages: English
• ISSNs: 0963-7486

Abstract

Abstract: There is an increasing interest in dietary polyphenols for risk reduction in cardiovascular diseases. The aim of this study was to evaluate acute and chronic flow-mediated dilation (FMD) and blood pressure responses to daily intake of boysenberry juice. FMD of the brachial artery was measured in six subjects in the initial, intermediate and follow-up stages of a 4-week open-label intervention study. The intake of boysenberry juice (180 ml/d) increased FMD with progression of intervention stage, and FMD differed in the follow-up stage compared with pre-intake baseline ( p = 0.0163 < 0.0167 = 0.1/6) using Bonferroni correction. Changes in systolic blood pressure (SBP) correlated negatively with SBP before intake only in the follow-up stage ( r = −0.961 and p = 0.0007 at 3.5 h), indicating a greater SBP reduction in subjects with higher SBP. These results suggest that daily intake of boysenberry juice is beneficial for reducing cardiovascular risk.