Granuloma faciale successfully treated with ingenol mebutate. Issue 5 (30th June 2016)

• Record Type: Journal Article
• Authors: Bobyr, I.; Campanati, A.; Consales, V.; Giangiacomi, M; Diotallevi, F.; Offidani, A.
• Is Part Of: Dermatologic therapy. Volume 29:Issue 5(2016)
• Page Start: 325
• Page End: 329
• Publication Date: 2016-06-30
• Subjects: granuloma faciale -- ingenol mebutate -- off label treatment; Skin -- Diseases -- Periodicals; Dermatology -- Periodicals; 616.5
• DOI: 10.1111/dth.12368
• Languages: English
• ISSNs: 1396-0296

Abstract

ABSTRACT: Granuloma faciale (GF) is a rare chronic inflammatory dermatosis of unknown etiology, characterized by leukocitoclastic vasculitis usually occurring on the face. We report a case of 60‐years‐old man with 3 year history of multiple actinic keratoses (AK) and persistent asymptomatic erythematous papules and plaques located over his left temporal region and the cheek: histopathology was consistent with GF. Herein we describe the successful treatment of the lesion with ingenol mebutate 0.015% gel focusing on the clinical, dermoscopic and histopathological findings of GF both before and after treatment.