Osteopenic features of the hip joint in patients with cerebral palsy: a hospital‐based study. (4th May 2016)

• Record Type: Journal Article
• Authors: Moon, Sang Young; Kwon, Soon‐Sun; Cho, Byung Chae; Chung, Chin Youb; Lee, Kyoung Min; Sung, Ki Hyuk; Chung, Myoung Ki; Zulkarnain, Arif; Kim, Yong Sung; Park, Moon Seok
• Is Part Of: Developmental medicine & child neurology. Volume 58:Number 11(2016:Nov.)
• Page Start: 1153
• Page End: 1158
• Publication Date: 2016-05-04
• Subjects: Child development -- Periodicals; Pediatric neurology -- Periodicals; 616.8
• DOI: 10.1111/dmcn.13146
• Languages: English
• ISSNs: 0012-1622

Abstract

Abstract : Aim: We aimed to evaluate the bone mineral density of the hip joint in patients with cerebral palsy (CP). Method: Patients with CP younger than 18 years who underwent three‐dimensional hip examination by computed tomography were analysed. Bone attenuation of the acetabulum and femur was measured as Hounsfield units (HU), and was adjusted for affecting factors such as hip instability and Gross Motor Function Classification System (GMFCS). Results: One hundred and twenty‐six patients with CP and 86 typically developing participants were included. The average bone attenuation was significantly lower in those with CP than in the comparison group (acetabulum: 70.8HU, 95% confidence interval [95% CI] 59.9–81.8; femur: 82.2HU, 95% CI 70.4–95.8). Compared with GMFCS levels I to III, bone attenuation was significantly lower for GMFCS levels IV (acetabulum: 30.9HU, 95% CI 15.7–46.2; femur: 39.7HU, 95% CI 19.9–59.5) and V (acetabulum: 51.7HU, 95% CI 35.9–67.5; femur: 72.5HU, 95% CI 51.9–93.0). The average bone attenuation decreased when the migration percentage was over 37% (acetabulum: 11.6HU, 95% CI 1.4–24.6; femur: 26.8HU, 95% CI 9.9–43.6). Interpretation: Bone attenuation of the acetabulum and femur was significantly affected both by GMFCS level and by severity of hip instability. What this paper adds: Average bone attenuation of the hip joint decreased as Gross Motor Function Classification System level increased. Bone density of the hip joint also decreased as hip instability worsened. This article is commented on by Rhodes and Blanchard on pages1103–1104 of this issue.