Cure for peritoneal metastases? An evidence‐based review. Issue 11 (1st July 2013)

• Record Type: Journal Article
• Authors: Ung, Lawson; Chua, Terence C.; Morris, David L.
• Is Part Of: ANZ journal of surgery. Volume 83:Issue 11(2013)
• Page Start: 821
• Page End: 826
• Publication Date: 2013-07-01
• Subjects: colorectal surgery -- surgical oncology; Surgery -- Periodicals; 617.005
• DOI: 10.1111/ans.12306
• Languages: English
• ISSNs: 1445-1433

Abstract

Abstract: There is now a considerable body of published evidence supporting the use of a multimodal approach consisting of cytoreductive surgery (CS) and heated intraperitoneal chemotherapy (HIPEC) in the treatment of peritoneal metastases (PM) arising from selected gastrointestinal tract malignancies. In the absence of systemic metastases, it is thought that disease confined to the peritoneum may be eradicated through optimum cytoreduction. This review critically evaluates the current body of published evidence for the use of CS/HIPEC in the treatment of advanced colorectal, appendiceal and gastric cancer. Although its role remains less defined in patients with gastric PM, current evidence provides a compelling argument for its use in PM of colorectal and appendiceal origin. With a low mortality and acceptable morbidity rate, CS/HIPEC may offer hope of long‐term survival and cure in a defined group of patients with this disease.