THE EVIDENCE FOR LATE-ONSET PRE-ECLAMPSIA AS A MATERNOGENIC DISEASE OF PREGNANCY. (19th March 2013)

• Record Type: Journal Article
• Authors: FERRAZZI, ENRICO; STAMPALIJA, TAMARA; AUPONT, JEAN EDGARD
• Is Part Of: Fetal and maternal medicine review. Volume 24:Number 1(2013)
• Page Start: 18
• Page End: 31
• Publication Date: 2013-03-19
• Subjects: Fetus -- Diseases -- Periodicals; Newborn infants -- Diseases -- Periodicals; Obstetrics -- Periodicals; Pregnancy -- Complications -- Periodicals; 618.3
• DOI: 10.1017/S0965539513000028
• Languages: English
• ISSNs: 0965-5395

Abstract

Abstract : It is our opinion that the evidence from epidemiological observations, clinical trials and biological studies is strong enough to support the view of different origin and phenotypes of pre-eclampsia: placental, which usually occurs (but not exclusively) early in pregnancy and is associated with poor early placentation of different severity with subsequent restriction of foetal growth, at different stages of gestation; and maternogenic, which generally occurs late in pregnancy and it is not related to placental insufficiency and foetal growth restriction.