A case of mottled hypopigmentation after low-fluence 1, 064-nm Q-switched neodymium-doped yttrium aluminum garnet laser therapy. (October 2013)

• Record Type: Journal Article
• Authors: Ryu, Hwa Jung; Kim, Jiehoon
• Is Part Of: Journal of cosmetic and laser therapy. Volume 15:Number 5(2013:Oct.)
• Page Start: 290
• Page End: 292
• Publication Date: 2013-10
• Subjects: lasers and light sources -- topical agents; Skin -- Laser surgery -- Periodicals; Surgery, Plastic -- Periodicals; 617.477
• DOI: 10.3109/14764172.2013.769762
• Languages: English
• ISSNs: 1476-4172

Abstract

Abstract: Melasma is a very difficult pigmented disease to treat with high recurrence rate. Using low-fluence 1, 064-nm Q-switched neodymium-doped yttrium aluminum garnet (QSNY) lasers repeatedly for the treatment of melasma is now a common practice in East Asia. However, one of the significant side effects is mottled hypopigmentation that appears as scattered white macules in the middle of melasma lesion. The pathophysiology of these hypopigmentation is yet unknown. The biopsy of the hypopigmented lesion showed decreased melanosome with intact melanocytes, and topical tretinoin may be the effective solution for these types of condition.