Facile green synthesis of calcium carbonate/folate porous hollow spheres for the targeted pH-responsive release of anticancer drugs. Issue 34 (2nd August 2016)

• Record Type: Journal Article
• Authors: Guo, Yuming; Jia, Weili; Li, Han; Shi, Weike; Zhang, Jie; Feng, Jing; Yang, Lin
• Is Part Of: Journal of materials chemistry. Volume 4:Issue 34(2016)
• Page Start: 5650
• Page End: 5653
• Publication Date: 2016-08-02
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c6tb01483f
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : Calcium carbonate/folate porous hollow spheres were prepared in a facile manner and used for the targeted delivery and pH-responsive sustained release of anticancer drugs. Abstract : Biocompatible hybrid hollow spheres of calcium carbonate/folate with both mesopores and macropores were synthesized using a facile green approach based on Ostwald ripening. The porous hollow spheres were efficiently loaded with doxorubicin, which they were then able to release in a pH-responsive and sustained manner for the targeted treatment of human cancer cells.