Anti‐TNF‐α for necrotizing sarcoid granulomatosis of the liver. Issue 4 (3rd February 2017)

• Record Type: Journal Article
• Authors: Sebode, Marcial; Weidemann, Sören; Wehmeyer, Malte; Lohse, Ansgar W.; Schramm, Christoph
• Is Part Of: Hepatology. Volume 65:Issue 4(2017)
• Page Start: 1410
• Page End: 1412
• Publication Date: 2017-02-03
• Subjects: Heart -- Diseases -- Nursing -- Periodicals; Lungs -- Diseases -- Nursing -- Periodicals; Intensive care nursing -- Periodicals; Foie -- Maladies -- Périodiques; 616.362
• DOI: 10.1002/hep.28966
• Languages: English
• ISSNs: 0270-9139

Abstract

Abstract : We present a case of hepatosplenic necrotizing sarcoid granulomatosis, a variant form of "classical" sarcoidosis, that became clinically apparent in the form of multiple hepatic and splenic masses mimicking malignancy. Flow cytometry of intrahepatic T cells isolated from liver biopsy led to the targeted treatment with anti‐tumor necrosis factor‐alpha, which was highly effective in inducing remission. (Hepatology 2017;65:1410‐1412)