Chitosan‐Gated Magnetic‐Responsive Nanocarrier for Dual‐Modal Optical Imaging, Switchable Drug Release, and Synergistic Therapy. Issue 6 (25th January 2017)

• Record Type: Journal Article
• Authors: Wang, Hui; Mu, Qingxin; Revia, Richard; Wang, Kui; Zhou, Xuezhe; Pauzauskie, Peter J.; Zhou, Shuiqin; Zhang, Miqin
• Is Part Of: Advanced healthcare materials. Volume 6:Issue 6(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-01-25
• Subjects: chitosan valve -- drug carriers -- multimodal imaging -- on/off release -- synergistic therapy; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201601080
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : A dual‐layer shell hollow nanostructure as drug carrier that provides instant on/off function for drug release and contrast enhancement for multimodal imaging is reported. The on‐demand drug release is triggered by irradiation of an external magnetic field. The nanocarrier also demonstrates a high drug loading capacity and synergistic magnetic‐thermal and chemotherapy.