Bactericidal, quorum quenching and anti-biofilm nanofactories: a new niche for nanotechnologists. (19th May 2017)

• Record Type: Journal Article
• Authors: Singh, Brahma N.; Prateeksha, ; Upreti, Dalip K.; Singh, Braj Raj; Defoirdt, Tom; Gupta, Vijai K.; De Souza, Ana Olivia; Singh, Harikesh Bahadur; Barreira, João C. M.; Ferreira, Isabel C. F. R.; Vahabi, Khabat
• Is Part Of: Critical reviews in biotechnology. Volume 37:Number 4(2017)
• Page Start: 525
• Page End: 540
• Publication Date: 2017-05-19
• Subjects: Antibacterial -- anti-biofilm -- nanomaterials -- nanotoxicology -- quorum quenching; Biotechnology -- Periodicals; Biotechnology -- Periodicals; Review Literature -- Periodicals; Public Health -- Periodicals; Environment -- Periodicals; Industry -- Periodicals; Biotechnology; Review Literature; Public Health; Environment; Industry; 660.6
• DOI: 10.1080/07388551.2016.1199010
• Languages: English
• ISSNs: 0738-8551

Abstract

Abstract: Despite several conventional potent antibacterial therapies, bacterial infections pose a significant threat to human health because they are emerging as the leading cause of death worldwide. Due to the development of antibiotic resistance in bacteria, there is a pressing demand to discover novel approaches for developing more effective therapies to treat multidrug-resistant bacterial strains and biofilm-associated infections. Therefore, attention has been especially devoted to a new and emerging branch of science "nanotechnology" to design non-conventional antimicrobial chemotherapies. A range of nanomaterials and nano-sized carriers for conventional antimicrobial agents have fully justified their potential to combat bacterial diseases by reducing cell viability, by attenuating quorum sensing, and by inhibiting/or eradicating biofilms. This communication summarizes emerging nano-antimicrobial therapies in treating bacterial infections, particularly using antibacterial, quorum quenching, and anti-biofilm nanomaterials as new approaches to tackle the current challenges in combating infectious diseases.