In vitro selection of random peptides against artificial lipid bilayers: a potential tool to immobilize molecules on membranes. Issue 24 (8th March 2017)

• Record Type: Journal Article
• Authors: Kobayashi, Shota; Terai, Takuya; Yoshikawa, Yuki; Ohkawa, Ryoya; Ebihara, Mika; Hayashi, Masahito; Takiguchi, Kingo; Nemoto, Naoto
• Is Part Of: Chemical communications. Volume 53:Issue 24(2017)
• Page Start: 3458
• Page End: 3461
• Publication Date: 2017-03-08
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc00099e
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The first in vitro selection of binding peptides against artificial lipid membranes was performed using a cDNA display method. Abstract : The first in vitro selection of binding peptides against artificial lipid membranes from a random peptide library using an in vitro display method (cDNA display) is reported. The selected peptide, LB-1, has both amphiphilic and cationic regions, and proteins fused to LB-1 can be immobilized on the liposome surface.