Sex-Based Differences in the Determinants of Old Age Life Expectancy: The Influence of Perimenopause. (2nd January 2017)

• Record Type: Journal Article
• Authors: Falconi, April M.
• Is Part Of: Biodemography and social biology. Volume 63:Number 1(2017)
• Page Start: 54
• Page End: 70
• Publication Date: 2017-01-02
• Subjects: Sociobiology -- Periodicals; Human biology -- Social aspects -- Periodicals; Demography -- Periodicals; Human evolution -- Periodicals; 304.5
• DOI: 10.1080/19485565.2016.1273755
• Languages: English
• ISSNs: 1948-5565

Abstract

ABSTRACT: Studies using the sensitive periods framework typically examine the effects of early life exposures on later life health, due to the significant growth and development occurring during the first few years of life. The menopausal transition (i.e., perimenopause) is similarly characterized by rapid physiological change, yet rarely has been tested as a sensitive window in adulthood. Cohort mortality data drawn from three historic populations, Sweden (1751–1919), France (1816–1919), and England and Wales (1841–1919), were analyzed using time series methods to assess whether conditions at midlife significantly influenced or "programmed" later life longevity. Results indicated a significant inverse association between mortality at ages 45–49, the average age range in which perimenopause occurred, and life expectancy at age 60 among females in all three countries. Study findings suggest a degree of plasticity associated with women's aging and, in particular, the age group correlated with perimenopause.