Metal-free synthesis of 3-methylthiofurans from homopropargylic alcohols and DMSO via a tandem sulfenylation/cyclization reaction in a one-pot manner. Issue 12 (6th October 2016)

• Record Type: Journal Article
• Authors: An, Zhenyu; She, Yue; Yang, Xiaodong; Pang, Xiaobo; Yan, Rulong
• Is Part Of: Organic chemistry frontiers. Volume 3:Issue 12(2017:Dec.)
• Page Start: 1746
• Page End: 1749
• Publication Date: 2016-10-06
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c6qo00462h
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A tandem sulfenylation/cyclization reaction for the synthesis of 3-methylthiofurans from homopropargylic alcohols and DMSO in a one-pot manner has been developed. Abstract : A tandem sulfenylation/cyclization reaction for the synthesis of 3-methylthiofurans from homopropargylic alcohols and DMSO in a one-pot manner has been developed. DMSO as a methylthiolation agent has been used for C–S bond formation in this process. Homopropargylic alcohols with various substituted groups proceed smoothly and the desired 3-methylthiofurans are obtained in moderate to good yields.