Out of the active site binding pocket for carbonic anhydrase inhibitors. Issue 2 (13th November 2014)
- Record Type:
- Journal Article
- Title:
- Out of the active site binding pocket for carbonic anhydrase inhibitors. Issue 2 (13th November 2014)
- Main Title:
- Out of the active site binding pocket for carbonic anhydrase inhibitors
- Authors:
- D'Ambrosio, Katia
Carradori, Simone
Monti, Simona M.
Buonanno, Martina
Secci, Daniela
Vullo, Daniela
Supuran, Claudiu T.
De Simone, Giuseppina - Abstract:
- Abstract : 2-Benzylsulfinylbenzoic acid binds to human carbonic anhydrase II in a mode completely different from any other class of carbonic anhydrase inhibitors investigated so far. Abstract : A structural study of the adduct which 2-benzylsulfinylbenzoic acid forms with human carbonic anhydrase II is reported, showing a binding mode completely different from any other class of carbonic anhydrase inhibitors investigated so far; this carboxylate binds in a pocket situated out of the enzyme active site.
- Is Part Of:
- Chemical communications. Volume 51:Issue 2(2015)
- Journal:
- Chemical communications
- Issue:
- Volume 51:Issue 2(2015)
- Issue Display:
- Volume 51, Issue 2 (2015)
- Year:
- 2015
- Volume:
- 51
- Issue:
- 2
- Issue Sort Value:
- 2015-0051-0002-0000
- Page Start:
- 302
- Page End:
- 305
- Publication Date:
- 2014-11-13
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c4cc07320g ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1376.xml