Europium functionalized ratiometric fluorescent transducer silicon nanoparticles based on FRET for the highly sensitive detection of tetracycline. Issue 8 (13th February 2017)

• Record Type: Journal Article
• Authors: Li, Xinran; Ma, Hong; Deng, Min; Iqbal, Anam; Liu, Xiaoyu; Li, Bo; Liu, Weisheng; Li, Jiping; Qin, Wenwu
• Is Part Of: Journal of materials chemistry. Volume 5:Issue 8(2017)
• Page Start: 2149
• Page End: 2152
• Publication Date: 2017-02-13
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Optical materials -- Research -- Periodicals; Electronics -- Materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c7tc00305f
• Languages: English
• ISSNs: 2050-7526

Abstract

Abstract : A europium functionalized silicon nanoparticle (SiNP) ratiometric fluorescence transducer based on FRET was designed to detect tetracycline (TC) with high sensitivity and selectivity. Abstract : A europium functionalized silicon nanoparticle (SiNP) ratiometric fluorescence transducer based on Fluorescence Resonance Energy Transfer (FRET) was designed to detect tetracyline (TC) as an effective antibiotic with high sensitivity and selectivity. SiNPs were prepared by one-step microwave-assisted synthesis from low-cost ethylenediaminetetraacetic acid disodium salt and (3-aminopropyl)triethoxysilane (APTES) as the precursor. The obtained SiNPs served as co-ligands for coordinating with Eu 3+ ions, energy donors in FRET, and also a fluorescence reference. The fluorescence intensity ratio of I 617 / I 450 of the transducer displayed a good linear response to TC concentrations in the range of 10 nM to 120 μM with a detection limit of 5.4 nM, and was applied successfully to determine the levels of TC in normal mouse sera and milk samples with high selectivity.