A robust second‐generation genome‐wide test for fetal aneuploidy based on shotgun sequencing cell‐free DNA in maternal blood. (3rd May 2013)
- Record Type:
- Journal Article
- Title:
- A robust second‐generation genome‐wide test for fetal aneuploidy based on shotgun sequencing cell‐free DNA in maternal blood. (3rd May 2013)
- Main Title:
- A robust second‐generation genome‐wide test for fetal aneuploidy based on shotgun sequencing cell‐free DNA in maternal blood
- Authors:
- Guex, N.
Iseli, C.
Syngelaki, A.
Deluen, C.
Pescia, G.
Nicolaides, K. H.
Xenarios, I.
Conrad, B. - Other Names:
- Chitty Lyn S. guestEditor.
Bianchi Diana W. guestEditor. - Abstract:
- Abstract : What's already known about this topic? Non‐invasive genome‐wide screening of fetal aneuploidy by shotgun sequencing cell‐free DNA in maternal blood has been shown to effectively identify fetal trisomy 21, but the performance of screening for other aneuploidies is variable. What does this study add? Optimizing all individual steps in the procedure and performing rigorous quality control provides a test capable of replacing invasive testing for the major aneuploidies.
- Is Part Of:
- Prenatal diagnosis. Volume 33:Number 7(2013:Jul.)
- Journal:
- Prenatal diagnosis
- Issue:
- Volume 33:Number 7(2013:Jul.)
- Issue Display:
- Volume 33, Issue 7 (2013)
- Year:
- 2013
- Volume:
- 33
- Issue:
- 7
- Issue Sort Value:
- 2013-0033-0007-0000
- Page Start:
- 707
- Page End:
- 710
- Publication Date:
- 2013-05-03
- Subjects:
- Prenatal diagnosis -- Periodicals
Fetus -- Diseases -- Diagnosis -- Periodicals
Electronic journals
618.32075 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/pd.4130 ↗
- Languages:
- English
- ISSNs:
- 0197-3851
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6607.646000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 571.xml