Conformational modulation of peptides using β-amino benzenesulfonic acid (SAnt). Issue 7 (18th December 2014)

• Record Type: Journal Article
• Authors: Priya, Gowri; Kotmale, Amol S.; Chakravarty, Debamitra; Puranik, Vedavati G.; Rajamohanan, Pattuparambil R.; Sanjayan, Gangadhar J.
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 7(2015)
• Page Start: 2087
• Page End: 2091
• Publication Date: 2014-12-18
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c4ob02421d
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : This communication describes the utility of the conformationally restricted aromatic β-amino acid (2-aminobenzenesulfonic acid, S Ant) for inducing various folding interactions in short peptides. Abstract : This communication describes the utility of a conformationally restricted aromatic β-amino acid (2-aminobenzenesulfonic acid, S Ant) inducing various folding interactions in short peptides. Sandwiching S Ant between diverse amino acid residues was shown to form robust folded architectures featuring a variety of H-bonded networks, suggesting its utility in inducing peptide folding.