Cd(ii)-terpyridine-based complex as a ratiometric fluorescent probe for pyrophosphate detection in solution and as an imaging agent in living cells. Issue 3 (25th November 2014)

• Record Type: Journal Article
• Authors: Jiao, Shu-Yan; Li, Kun; Zhang, Wei; Liu, Yan-Hong; Huang, Zeng; Yu, Xiao-Qi
• Is Part Of: Dalton transactions. Volume 44:Issue 3(2015)
• Page Start: 1358
• Page End: 1365
• Publication Date: 2014-11-25
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c4dt03022b
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : A ratiometric fluorescent probe for Cd 2+ based terpyridine anthracene ligandL1 was synthesized and characterized. The results suggested that the probe could be successfully applied in Cd 2+ and pyrophosphate sensing in living cells. Abstract : The terpyridine anthracene ligandL1 was synthesized and characterized.L1 is a ratiometric fluorescent probe for Cd 2+ with a recognition mechanism based on intramolecular charge transfer (ICT). AnL1-Cd(ii ) complex was isolated, and its structure was established using single-crystal XRD. TheL1-Cd(ii ) complex was able to serve as a novel reversible chemosensing ensemble to allow ratiometric response to pyrophosphate (PPi) in aqueous media. Moreover, the fluorescence imaging in living cells from these two emission channels suggested thatL1 was a ratiometric probe for Cd 2+, and the in situ generatedL1-Cd(ii ) complex was also a ratiometric ensemble for PPi detection in living cells.