Cellular activity of siRNA oligonucleotides containing synthetic isomorphic nucleoside surrogates. Issue 9 (15th December 2014)
- Record Type:
- Journal Article
- Title:
- Cellular activity of siRNA oligonucleotides containing synthetic isomorphic nucleoside surrogates. Issue 9 (15th December 2014)
- Main Title:
- Cellular activity of siRNA oligonucleotides containing synthetic isomorphic nucleoside surrogates
- Authors:
- Shin, Dongwon
Lönn, Peter
Dowdy, Steven F.
Tor, Yitzhak - Abstract:
- Abstract : Singly and multiply modified synthetic siRNA oligonucleotides, containing highly isomorphic surrogate nucleobases, show high interference activity in cell culture. Abstract : Singly and multiply modified synthetic siRNA oligonucleotides, containing isomorphic surrogate nucleobases, show high interference potency in cell culture, suggesting the highly isomorphic RNA alphabet, based on a thieno[3, 4- d ]-pyrimidine core, is tolerated well by the cellular silencing machinery.
- Is Part Of:
- Chemical communications. Volume 51:Issue 9(2015)
- Journal:
- Chemical communications
- Issue:
- Volume 51:Issue 9(2015)
- Issue Display:
- Volume 51, Issue 9 (2015)
- Year:
- 2015
- Volume:
- 51
- Issue:
- 9
- Issue Sort Value:
- 2015-0051-0009-0000
- Page Start:
- 1662
- Page End:
- 1665
- Publication Date:
- 2014-12-15
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c4cc08809c ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 944.xml