Direct and metal-free arylsulfonylation of alkynes with sulfonylhydrazides for the construction of 3-sulfonated coumarins. Issue 4 (25th November 2014)

• Record Type: Journal Article
• Authors: Wei, Wei; Wen, Jiangwei; Yang, Daoshan; Guo, Mengyuan; Wang, Yingying; You, Jinmao; Wang, Hua
• Is Part Of: Chemical communications. Volume 51:Issue 4(2015)
• Page Start: 768
• Page End: 771
• Publication Date: 2014-11-25
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c4cc08117j
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A novel and metal-free procedure has been developed for the construction of sulfonated coumarins via direct arylsulfonylation of alkynes with sulfonylhydrazides. Abstract : A novel and metal-free procedure has been developed for the construction of 3-sulfonated coumarins via the direct difunctionalization of alkynoates with sulfonylhydrazides. The present protocol, which simply utilizes TBAI as the catalyst and TBHP as the oxidant, provides a convenient and highly efficient approach to construct a series of sulfonated coumarins with high regioselectivity and good functional group tolerance.