Three salts from the reactions of cysteamine and cystamine with L‐(+)‐tartaric acid. (16th May 2013)

• Record Type: Journal Article
• Authors: Benylles, Amina; Cairns, Donald; Cox, Philip J.; Kay, Graeme
• Is Part Of: Acta crystallographica. Volume 69:Part 6(2013:Jun.)
• Page Start: 658
• Page End: 664
• Publication Date: 2013-05-16
• Subjects: Crystallography -- Periodicals; Crystals -- Periodicals; 548.05
• DOI: 10.1107/S0108270113012377
• Languages: English
• ISSNs: 0108-2701

Abstract

Abstract : Reaction between cysteamine (systematic name: 2‐aminoethanethiol, C2 H7 NS) and L‐(+)‐tartaric acid [systematic name: (2 R, 3 R )‐2, 3‐dihydroxybutanedioic acid, C4 H6 O6 ] results in a mixture of cysteamine tartrate(1−) monohydrate, C2 H8 NS + ·C4 H5 O6 − ·H2 O, (I), and cystamine bis[tartrate(1−)] dihydrate, C4 H14 N2 S2 2+ ·2C4 H5 O6 − ·2H2 O, (III). Cystamine [systematic name: 2, 2′‐dithiobis(ethylamine), C4 H12 N2 S2 ], reacts with L‐(+)‐tartaric acid to produce a mixture of cystamine tartrate(2−), C4 H14 N2 S2 2+ ·C4 H4 O6 2−, (II), and (III). In each crystal structure, the anions are linked by O—H...O hydrogen bonds that run parallel to the a axis. In addition, hydrogen bonding involving protonated amino groups in all three salts, and water molecules in (I) and (III), leads to extensive three‐dimensional hydrogen‐bonding networks. All three salts crystallize in the orthorhombic space group P 21 21 21 .