Bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution. Issue 2 (18th November 2014)

• Record Type: Journal Article
• Authors: Nishihara, Ryo; Suzuki, Hideyuki; Hoshino, Emi; Suganuma, Sakura; Sato, Moritoshi; Saitoh, Tsuyoshi; Nishiyama, Shigeru; Iwasawa, Naoko; Citterio, Daniel; Suzuki, Koji
• Is Part Of: Chemical communications. Volume 51:Issue 2(2015)
• Page Start: 391
• Page End: 394
• Publication Date: 2014-11-18
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c4cc06886f
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Coelenterazine derivatives with extended substituents show significant bioluminescence emission with known renilla luciferase variants, indicating a promising method to develop substrates with superior optical properties. Abstract : Three novel coelenterazine (CTZ) derivatives with extension at the C-6 position of the imidazopyrazinone structure show significant bioluminescence emission with known renilla luciferase variants, indicating a promising method to develop CTZ derivatives with superior optical properties compared to hitherto reported compounds.