Cu-Catalyzed selective C3-formylation of imidazo[1, 2-a]pyridine C–H bonds with DMSO using molecular oxygen. Issue 10 (18th December 2014)

• Record Type: Journal Article
• Authors: Cao, Hua; Lei, Sai; Li, Naiying; Chen, Longbin; Liu, Jingyun; Cai, Huiyin; Qiu, Shuxian; Tan, Jingwen
• Is Part Of: Chemical communications. Volume 51:Issue 10(2015)
• Page Start: 1823
• Page End: 1825
• Publication Date: 2014-12-18
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c4cc09134e
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Using the widely available DMSO as the formylation reagent under oxidative conditions, an efficient Cu-catalyzed C3-formylation reaction of imidazo [1, 2- a ]pyridine C–H bonds to directly generate structurally sophisticated 3-formyl imidazo[1, 2- a ]pyridine derivatives has been developed. Abstract : Using the widely available DMSO as the formylation reagent under oxidative conditions, an efficient Cu-catalyzed C3-formylation reaction of imidazo[1, 2- a ]pyridine C–H bonds to directly generate structurally sophisticated 3-formyl imidazo[1, 2- a ]pyridine derivatives has been developed. The reaction proceeded to generate products in good yields, and used the environmentally friendly molecular oxygen as the oxidant.