Fabricating polyacrylamide microbeads by inverse emulsification to mimic the size and elasticity of living cells. (9th December 2016)

• Record Type: Journal Article
• Authors: Labriola, Nicholas R.; Mathiowitz, Edith; Darling, Eric M.
• Is Part Of: Biomaterials science. Volume 5:Number 1(2017:Jan.)
• Page Start: 41
• Page End: 45
• Publication Date: 2016-12-09
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1039/c6bm00692b
• Languages: English
• ISSNs: 2047-4830

Abstract

Abstract : Inverse emulsification was used to fabricate polyacrylamide (PAAm) microbeads with size and elastic properties similar to typical, mammalian cells. Abstract : Inverse emulsification was used to fabricate polyacrylamide (PAAm) microbeads with size and elastic properties similar to typical, mammalian cells. These biomimicking microbeads could be fluorescently stained and functionalized with a collagen type-I coating, post-polymerization, for tracking bead locations and promoting cell recognition/binding, respectively. By occupying a previously unfilled range of sizes and mechanical properties, these microbeads may find unique use in both biomedical and materials applications.