Expression analysis of a family of developmentally‐regulated cytosolic sulfotransferases (SULTs) in Drosophila. Issue 2 (22nd May 2013)

• Record Type: Journal Article
• Authors: Fahmy, Khalid; Baumgartner, Stefan
• Is Part Of: Hereditas. Volume 150:Issue 2/3(2013:Apr.)
• Page Start: 44
• Page End: 48
• Publication Date: 2013-05-22
• Subjects: Heredity -- Periodicals; Genetics -- Periodicals; Cytogénétique; Génétique; Hérédité; Périodique électronique (Descripteur de forme); Ressource Internet (Descripteur de forme); 576.5
• DOI: 10.1111/j.1601-5223.2013.00006.x
• Languages: English
• ISSNs: 0018-0661

Abstract

Abstract : We have compared the amino acid sequence of all four cytosolic sulfotransferases (SULTs) in Drosophila and analyzed their spatial expression patterns during development. Three out of four SULTs show distinct expression activity during embryogenesis, while the 4th SULT shows expression only post‐embryonically. st1, st3 and st4 are expressed in non‐overlapping expression domains mainly confined to organs of the alimentary canal such as esophagus, malphigian tubules, hindgut, as well as in the tracheal system. All these organs are surrounded by the hemolymph suggesting that Drosophila SULTs exert their function in detoxification of substances upon influx from the hemolymph.