6-exo-trig Michael addition-lactonizations for catalytic enantioselective chromenone synthesis. Issue 17 (30th January 2017)
- Record Type:
- Journal Article
- Title:
- 6-exo-trig Michael addition-lactonizations for catalytic enantioselective chromenone synthesis. Issue 17 (30th January 2017)
- Main Title:
- 6-exo-trig Michael addition-lactonizations for catalytic enantioselective chromenone synthesis
- Authors:
- Neyyappadath, Rifahath M.
Cordes, David B.
Slawin, Alexandra M. Z.
Smith, Andrew D. - Abstract:
- Abstract : The catalytic enantioselective 6- exo -trig Michael addition-lactonization of enone-acid substrates to form cis -chromenones with high diastereo- and enantiocontrol was developed using the commercially available isothiourea tetramisole. Abstract : The catalytic enantioselective 6- exo -trig Michael addition-lactonization of enone-acid substrates to form cis -chromenones with high diastereo- and enantiocontrol was developed using the commercially available isothiourea tetramisole. An acidic workup proved necessary to minimize product epimerization and maximize product er, providing cis -chromenones in excellent yield, and with excellent diastereo- and enantioselectivity.
- Is Part Of:
- Chemical communications. Volume 53:Issue 17(2017)
- Journal:
- Chemical communications
- Issue:
- Volume 53:Issue 17(2017)
- Issue Display:
- Volume 53, Issue 17 (2017)
- Year:
- 2017
- Volume:
- 53
- Issue:
- 17
- Issue Sort Value:
- 2017-0053-0017-0000
- Page Start:
- 2555
- Page End:
- 2558
- Publication Date:
- 2017-01-30
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c6cc10178j ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 2181.xml