Mechanistic insights into transient severe mitral regurgitation. (3rd July 2015)

• Record Type: Journal Article
• Authors: Liang, Jackson J.; Syed, Faisal F.; Killu, Ammar M.; Boilson, Barry A.; Nishimura, Rick A.; Pislaru, Sorin V.
• Is Part Of: Acute cardiac care. Volume 17:Number 3(2015)
• Page Start: 41
• Page End: 44
• Publication Date: 2015-07-03
• Subjects: Mitral regurgitation -- ischemia -- vasospasm -- echo cardiography -- catheterization; Cardiac intensive care -- Periodicals; Cardiovascular system -- Diseases -- Treatment -- Periodicals; 616.12028
• DOI: 10.3109/17482941.2015.1110243
• Languages: English
• ISSNs: 1748-2941

Abstract

Abstract : Acute mitral regurgitation (AMR), a known complication of acute coronary syndromes, is usually associated with posterior papillary muscle dysfunction/rupture. In severe cases, management of AMR requires surgical intervention. Reversible severe AMR in patients in the absence of left ventricular systolic dysfunction and coronary artery stenosis may result from processes which cause transient subendocardial ischemia, such as intermittent episodes of hypotension or coronary artery vasospasm. We present two cases of reversible transient AMR due to subendocardial and/or endocardial ischemia, both of which offer insight into the mechanism of transient severe AMR.