Chemotherapy‐induced prospective memory impairment in patients with breast cancer. Issue 10 (15th May 2013)

• Record Type: Journal Article
• Authors: Cheng, Huaidong; Yang, Zhen; Dong, Biao; Chen, Chanjuan; Zhang, Mingjun; Huang, Zhonglian; Chen, Zhendong; Wang, Kai
• Is Part Of: Psycho-oncology. Volume 22:Issue 10(2013)
• Page Start: 2391
• Page End: 2395
• Publication Date: 2013-05-15
• Subjects: cancer -- chemotherapy -- cognitive -- oncology -- prospective memory; Cancer -- Psychological aspects -- Periodicals; Cancer -- Social aspects -- Periodicals; Neoplasms -- psychology -- Periodicals; 616.9940019
• DOI: 10.1002/pon.3291
• Languages: English
• ISSNs: 1057-9249

Abstract

Abstract: Objective: This study aimed to investigate the event‐based prospective memory (EBPM) and time‐based prospective memory (TBPM) in chemotherapy‐induced cognitive impairment in patients with breast cancer. Methods: Forty patients with breast cancer who underwent adjuvant chemotherapy and 40 age‐matched and education‐matched healthy women were administered with a battery of neuropsychological tests including EBPM and TBPM tasks. Results: A significant difference between breast cancer patients and controls was found in the scores on the mini‐mental state examination ( t = −11.684, p < 0.01), verbal fluency test ( t = −7.939, p < 0.01), and digit span ( t = −2.538, p < 0.05). Compared with healthy controls, breast cancer patients exhibited a poorer performance on EBPM ( t = −7.096, p < 0.01) but not on TBPM ( t = −1.921, p > 0.05). Conclusions: Our results suggest that breast cancer patients who had undergone adjuvant chemotherapy show deficits in EBPM but not in TBPM. Copyright © 2013 John Wiley & Sons, Ltd.