Long‐term health‐related quality of life in living liver donors: A south Asian experience. Issue 3 (15th February 2017)

• Record Type: Journal Article
• Authors: Cherian, P. Thomas; Mishra, Ashish Kumar; Mahmood, S. M. Faisal; Sathyanarayanan, Mohan; Raya, Ravichandra; Kota, Venugopal; Rela, Mohamed S.
• Is Part Of: Clinical transplantation. Volume 31:Issue 3(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-02-15
• Subjects: biliary complications -- complications -- donor hepatectomy -- follow‐up -- HRQOL -- outcomes; Transplantation of organs, tissues, etc -- Periodicals; 617.95
• DOI: 10.1111/ctr.12882
• Languages: English
• ISSNs: 0902-0063

Abstract

Abstract: Aim: The aim of this study was to evaluate long‐term health‐related quality of life (HRQOL), changes in lifestyle, and complications in living liver donors at a single transplant center from southern India. Methods: A total of 64 consecutive living liver donors from 2008 to 2011 were evaluated; 46 of 64 donors completed the short form 36 (SF‐36) via telephonic interviews or clinic consultations. Mean follow‐up was 48 months (range: 37‐84 months). Results: There was no mortality in the donors evaluated. Overall morbidity was 23%, which included wound infections (4.3%), incisional hernia (2.1%), biliary leak (4.3%), and nonspecific complaints regarding the incision site (15.2%). All 46 donors who completed the SF‐36 had no change in career path or predonation lifestyle. A total of 40 of 46 (87%) donors had no limitations, decrements, or disability in any domain, while six of 46 (13%) had these in some domains of which general health (GH) was most severely affected. Conclusions: Living donor hepatectomy is safe with acceptable morbidity and excellent long‐term HRQOL with no change in career path or significant alteration of lifestyle for donors.