Nanostructured luminescently labeled nucleic acids. (15th July 2016)

• Record Type: Journal Article
• Authors: Kricka, Larry J.; Fortina, Paolo; Park, Jason Y.
• Is Part Of: Luminescence. Volume 32:Number 2(2017)
• Page Start: 132
• Page End: 141
• Publication Date: 2016-07-15
• Subjects: nucleic acid labeling -- chemiluminescence -- photoluminescence -- electrochemiluminescence -- nanostructures; Luminescence -- Periodicals; Bioluminescence -- Periodicals; Chemiluminescence -- Periodicals; Luminescence -- Periodicals; 535.35
• DOI: 10.1002/bio.3170
• Languages: English
• ISSNs: 1522-7235

Abstract

Abstract: Important and emerging trends at the interface of luminescence, nucleic acids and nanotechnology are: (i) the conventional luminescence labeling of nucleic acid nanostructures (e.g. DNA tetrahedron); (ii) the labeling of bulk nucleic acids (e.g. single‐stranded DNA, double‐stranded DNA) with nanostructured luminescent labels (e.g. copper nanoclusters); and (iii) the labeling of nucleic acid nanostructures (e.g. origami DNA) with nanostructured luminescent labels (e.g. silver nanoclusters). This review surveys recent advances in these three different approaches to the generation of nanostructured luminescently labeled nucleic acids, and includes both direct and indirect labeling methods.