Improvement of erythema dyschromicum perstans using a combination of the 1, 550‐nm erbium‐doped fractionated laser and topical tacrolimus ointment. Issue 1 (23rd August 2016)

• Record Type: Journal Article
• Authors: Wolfshohl, Jon A.; Geddes, Elizabeth R.C.; Stout, Ashlyn B.; Friedman, Paul M.
• Other Names: Manstein Dieter guestEditor.
• Is Part Of: Lasers in surgery and medicine. Volume 49:Issue 1(2017)
• Page Start: 60
• Page End: 62
• Publication Date: 2016-08-23
• Subjects: erythema dyschromicum perstans -- edp -- pigmentary disorder -- pigment disorder -- nonablative 1550 nm erbium‐doped fractionated laser -- fraxel -- ashy dermatosis -- laser; Lasers in medicine -- Periodicals; Lasers in surgery -- Periodicals; 617
• DOI: 10.1002/lsm.22567
• Languages: English
• ISSNs: 0196-8092

Abstract

Abstract : Background and Objective: Erythema dyschromicum perstans (EDP) is a cosmetically distressing, acquired pigmentary disorder of unknown etiology for which few successful therapies exist. Herein, we present the successful use of non‐ablative fractional photothermolysis in combination with topical tacrolimus ointment. Study Design/Patients and Methods: A 35‐year‐old female with biopsy‐confirmed EDP underwent a series of fractionated non‐ablative treatment sessions utilizing the 1, 550 nm erbium‐doped fiber laser in combination with topical tacrolimus ointment over a period of 5 months. Results: The patient's EDP improved by greater than 75% and results were maintained at the 8‐month follow‐up visit. Conclusion: The combination of non‐ablative fractional photothermolysis and topical tacrolimus ointment is a potential safe and effective therapeutic option for erythema dyschromicum perstans. Additional prospective, comparative studies are warranted. Lasers Surg. Med. 49:60–62, 2017. © 2016 Wiley Periodicals, Inc.