Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response. Issue 4 (27th December 2016)

• Record Type: Journal Article
• Authors: Patel, Dharmesh; Sharma, Sadhana; Bryant, Stephanie J.; Screen, Hazel R. C.
• Is Part Of: Advanced healthcare materials. Volume 6:Issue 4(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2016-12-27
• Subjects: fiber composites -- mechanical properties -- mechanotransduction -- poly(ethylene glycol) -- tenocyte; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201601095
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : A fiber composite system is presented which recapitulates the fiber‐composite‐like nature of tissues and generates similar modes of shear and tension. The shear/tension ratio can be customized during composite manufacture and incorporates viable cells. The system is a valuable tool for mechanotransduction research, providing a platform with physiologically relevant conditions for investigating cell behavior in different tissue types.