Endoscopic therapy in the treatment of caustic esophageal stricture: A retrospective case series study. Issue 5 (26th December 2012)

• Record Type: Journal Article
• Authors: Zhang, Cuiling; Zhou, Xiaoying; Yu, Lianzhen; Ding, Jing; Shi, Ruihua
• Is Part Of: Digestive endoscopy. Volume 25:Issue 5(2013:Sep.)
• Page Start: 490
• Page End: 495
• Publication Date: 2012-12-26
• Subjects: balloon dilatation -- bougie dilatation -- caustic esophageal stricture -- endoscopic therapy -- esophageal stenting; Digestive organs -- Diseases -- Periodicals; Digestive organs -- Diseases -- Diagnosis -- Periodicals; Endoscopy -- Periodicals; Digestive System Diseases -- diagnosis -- Periodicals; Digestive System Diseases -- therapy -- Periodicals; Endoscopy -- Periodicals; 616.3
• DOI: 10.1111/den.12023
• Languages: English
• ISSNs: 0915-5635

Abstract

Abstract : Background: Endoscopic procedures, such as balloon/bougie dilation and stent implantation, have gained increasing potential as the treatment of corrosive esophageal stricture. The purpose of the present retrospective case series study was to assess clinical outcomes of endoscopic therapy of esophageal strictures after caustic injury. Patients and Methods: Between January 2003 and December 2009, 13 admitted patients that developed esophageal stricture after caustic agent ingestion underwent endoscopic therapy at the First Affiliated Hospital of Nanjing Medical University. Data such as age, gender, caustic agents, site of burn, type of treatment, effectiveness and outcome of endoscopic therapy were recorded. Results: The average follow up was 39 months with a range of 29–70 months. Successful endoscopic therapy was achieved in 12 of 13 patients (92%). Duration of stricture resolution was between 4 and 48 months (mean, 15 months). Among them, seven patients required dilations only, whereas the other five patients received both dilations and stent implantation. There were no severe complications in these patients. Conclusions: These data suggest that endoscopic therapy is feasible, less invasive and effective for the management of caustic esophageal stricture. After repeat dilation and stenting, patients can achieve stricture resolution in approximately 15 months and avoid surgery.